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In 1507 Martin Waldseemüller published a world map, Universalis Cosmographia , which was the first to show North and South America as separate from Asia and surrounded by water. A small inset map above the main map explicitly showed for the first time the Americas being east of Asia and separated from Asia by an ocean, as opposed to just placing the Americas on the left end of the map and Asia on the right end. In the accompanying book Cosmographiae Introductio , Waldseemüller noted that the earth is divided into four parts, Europe, Asia, Africa and the fourth part, which he named "America" after Amerigo Vespucci's first name.  On the map, the word "America" was placed on part of South America.
VIEKIRA PAK with ribavirin was assessed in 34 post-liver transplant subjects with recurrent HCV infection. Adverse events occurring in more than 20% of subjects included fatigue 50%, headache 44%, cough 32%, diarrhea 26%, insomnia 26%, asthenia 24%, nausea 24%, muscle spasms 21% and rash 21%. Ten subjects (29%) had at least one post-baseline hemoglobin value of less than 10 g/dL. Ten subjects underwent a ribavirin dose modification due to decrease in hemoglobin and 3% (1/34) had an interruption of ribavirin. Five subjects received erythropoietin, all of whom initiated ribavirin at the starting dose of 1000 to 1200 mg daily. No subject received a blood transfusion [see Clinical Studies ].