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Cryo-EM uses liquid ethane to flash freeze molecules in midmovement in water. Researchers then view them under an electron microscope and employ computer programs to sort the images and assemble the data into a coherent structure. Unlike x-ray crystallography—the gold standard of structural biology—cryo-EM doesn’t require target molecules to be crystallized, often a difficult task, and because it catches them midstride, it can reveal clues to function. The technique’s roots go back decades, but improvements in instrumentation, software to speed up image processing and analysis, and new quality standards in the works to reduce errors have helped touch off an explosion of advances.

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Farmacos corticoesteroides clasificacion

farmacos corticoesteroides clasificacion

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