Cryo-EM uses liquid ethane to flash freeze molecules in midmovement in water. Researchers then view them under an electron microscope and employ computer programs to sort the images and assemble the data into a coherent structure. Unlike x-ray crystallography—the gold standard of structural biology—cryo-EM doesn’t require target molecules to be crystallized, often a difficult task, and because it catches them midstride, it can reveal clues to function. The technique’s roots go back decades, but improvements in instrumentation, software to speed up image processing and analysis, and new quality standards in the works to reduce errors have helped touch off an explosion of advances.
The company´s business model is based on four different areas, . R&D, Contract Manufacturing and Contract Development (CDMO), Licensing In & Out and Commercialization. This is affordable by a continuous investment in research and innovative technologies and a wide experienced team of employees most of which are highly trained and possess a bachelor, master or PhD. In addition, GP Pharm’s state of art manufacturing facilities have been widely approved by different Regulatory Agencies –including EU, US or Japan– allowing the firm to be position in a worldwide setting.