Shingles can be very painful and itchy. It is not very dangerous to healthy people, and it usually ends without major problems. The rash and pain last 3 to 5 weeks. Sometimes, serious problems like temporary, partial facial paralysis , ear damage, or encephalitis may occur. Persons with shingles on the upper half of the face need immediate medical attention: the virus may cause serious damage to the eyes . Most people who have shingles have only one attack of the disease in their lifetime. However, people with AIDS , cancer or weak immune systems may have multiple attacks.
The number of new cases a year of acute encephalitis in Western countries is cases per 100,000 population per year. In tropical countries, the incidence is per 100,000 per year.  The incidence of Encephalitis has not changed much over time, with an incidence of encephalitis in the US of 250,000 from 2005 to 2015. Approximately seven per 100,000 patients were hospitalized for encephalitis in the US during this time.  In 2015, encephalitis was estimated to have affected million people and resulted in 150,000 deaths worldwide.   Herpes simplex encephalitis has an incidence of 2–4 per million population per year. 
Squamous cell carcinoma (SCC or SqCC), occasionally rendered as “squamous-cell carcinoma”, is a histologically-distinct form of cancer. It arises from the uncontrolled multiplication of transformed malignant cells showing squamous differentiation and tissue architecture. Squamous cell carcinoma is one of the most common cancers, and frequently forms in a large number of body tissues and organs, including skin, lips, mouth, esophagus, urinary bladder, prostate, lung, vagina, and cervix, among others. Despite the common name, squamous cell carcinomas often show large differences, depending on where they develop, in their presentation, natural history, prognosis, and response to treatment