Non steroidal anti inflammatory drug definition

NSAIDs have anti-inflammatory (reduce inflammation), analgesic (relieve pain) and antipyretic (lower temperature) effects. Although different NSAIDs have different structures, they all work by blocking cyclooxygenase (COX) enzymes. There are two main types of COX enzymes: COX-1 and COX-2. Both types produce prostaglandins; however, the main function of COX-1 enzymes is to produce baseline levels of prostaglandins that activate platelets and protect the lining of the gastrointestinal tract, whereas COX-2 enzymes are responsible for releasing prostaglandins after infection or injury. Prostaglandins have a number of different effects, one of which is to regulate inflammation. Most NSAIDs inhibit both enzymes, although a few are available that mainly inhibit COX-2. The pain-relieving and anti-inflammatory effects of NSAIDs are mainly due to inhibition of COX-2, and their unwanted side effects are largely due to inhibition of COX-1.

While NSAIDs can potentially cause many side effects – some of which may be serious or life-threatening – if prescribed under the right conditions and used as instructed, they can be of great benefit. Your doctor can help you consider the benefits and risks of taking an NSAID to ensure they’re the right treatment option for you.

When you’re taking an NSAID, always use it cautiously and for the shortest time possible. If you need to use these medicines for a long time (for example, to manage the symptoms of arthritis when other therapies don’t offer relief, or when you’re taking low-dose aspirin to prevent a heart attack or stroke), make sure you see your doctor regularly.

Do not wait for things to get worse before you decide to see a doctor. Non-steroidal anti-inflammatory drugs work, but remember that they are only for short-term use. If your back pain keeps on recurring or if it gets worse, you better see a doctor who is specialized in treating back pain and other similar issues. You need to go to a place solely dedicated in providing pain management solutions. That is no other than Arizona Pain and Spine Institute. We provide relief through various treatment options and approaches, for different pain issues. Make an appointment with us today.

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  • Citation tools Download this article to citation manager Arfè Andrea , Scotti Lorenza , Varas-Lorenzo Cristina , Nicotra Federica , Zambon Antonella , Kollhorst Bianca et al. Non-steroidal anti-inflammatory drugs and risk of heart failure in four European countries: nested case-control study BMJ 2016; 354 :i4857
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    Non steroidal anti inflammatory drug definition

    non steroidal anti inflammatory drug definition

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  • Citation tools Download this article to citation manager Arfè Andrea , Scotti Lorenza , Varas-Lorenzo Cristina , Nicotra Federica , Zambon Antonella , Kollhorst Bianca et al. Non-steroidal anti-inflammatory drugs and risk of heart failure in four European countries: nested case-control study BMJ 2016; 354 :i4857
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