Once the disease is initially treated and under control, the dog will need to receive replacement hormones for the rest of their life. There is no cure for Addison’s disease. Dosage may need to be frequently adjusted, especially at first, by a veterinarian. Florinef is the most commonly prescribed drug for Addison’s disease and is given twice a day. DOCP is a newer injection treatment given once every 25 days that is also effective. These medications may be supplemented, and your veterinarian can give you specific instructions for your dog. The good news is that, with proper treatment and monitoring, a dog with Addison’s disease has the same life expectancy as one without the disease.