Availability of neutral spirit for retail purchase varies between states. States where consumer sales of high-ABV neutral spirit are prohibited include Florida,  Maine, [ citation needed ] Minnesota,  Nevada,  North Carolina,  Ohio, Pennsylvania,  and West Virginia.  In Virginia, the purchase of neutral spirits requires a no-cost "Grain Alcohol Permit", issued "strictly for industrial, commercial, culinary or medicinal use".  In 2017 Virginia has approved the sale of up to 151 proof neutral spirits at its ABC stores without a permit. 
Omega-3 and omega-6 fatty acids are considered to be nutritionally essential but cannot be synthesised by humans and animals. The balance of these two fatty acids is important for health and longevity rather than the absolute amount, therefore this study focused on evaluating the dietary supplementation of varying ratios of omega-6 : omega-3 fatty acids (15 : 1, 10 : 1 and 5 : 1) on the performance, nutrient digestibility, immune status and faecal microbiota of weaner pigs. As a result of this study, the reduction of the omega-6 : omega-3 fatty acid ratio from 15 : 1 to 5 : 1 in the diet showed a positive effect on the growth performance of pigs during phases 1 and 2; dry matter, nitrogen and energy digestibility and HDL cholesterol concentration increased linearly during week 3 but no effect on faecal microbiota were observed with the reduction of the omega-6 : omega-3 FA ratio from 15 : 1 to 5 : 1, indicating that the ratio of 5 : 1 is beneficial to weaner pigs.