Treating rheumatoid arthritis with steroids

Patients in the MTX monotherapy group were twice as likely to discontinue from the study due to adverse events compared to patients in the placebo group, at 12 to 52 weeks (16% versus 8%; RR , 95% CI to ; NNT 13, 95% CI 6 to 44). Compared to placebo, nine more people out of 100 who took MTX withdrew from the studies because of side effects (ATB 9%, 95% CI 3% to 14%). Total adverse event rates at 12 weeks were higher in the MTX monotherapy group compared to the placebo group (45% versus 15%; RR , 95% CI to ; NNT 4, 95% CI 2 to 17). Thirty more people out of 100 who took MTX compared to those who took placebo experienced any type of side effect (common or rare) (ATB 30, 95% CI 13% to 47%). No statistically significant differences were observed in the total number of serious adverse events between the MTX group and the placebo group at 27 to 52 weeks. Three people out of 100 who took MTX alone experienced rare but serious side effects compared to 2 people out of 100 who took a placebo (3% versus 2%, respectively).

Different forms of arthritis have different root causes. Rheumatoid arthritis and psoriatic arthritis are examples of “inflammatory arthritis,” also described as autoimmune arthritis. This occurs when the immune system generates internal inflammation to get rid of perceived threats (like an infection or allergy) and mistakenly causes joint erosion and sometimes organ damage. These forms of arthritis are especially important to treat as early on as possible, since tissue damage can be hard to reverse once it sets in. Inflammatory arthritis is believed to be highly tied to gut health, which means a healthy diet is key for recovery.

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about quinapril. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using quinapril.

Treating rheumatoid arthritis with steroids

treating rheumatoid arthritis with steroids

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