Simultaneous initial involvement of cortical and spinal motor neurons responsible for the same body part in ALS and the independent spread of disease at spinal and cortical levels has been shown. [ 60 ] These observations have been replicated, [ 61 ] although other patterns of spread are sometimes seen. They establish an irrefutable role for corticospinal neurons in the early spread of ALS and provide an observational foundation for postulating the existence of a focus of onset and one or more "agents of spread." [ 62 ]
Rodriguez is the former owner of the Iron Addicts Gym in Miami, and Bravo has been working on a film to uncover the mystery behind the gym. The DEA arrested Rodriguez and raided the gym in February 2017 following an investigation. Rodriguez was accused of being involved in a distribution chain that imported goods from China, then manufactured illegal steroids in Arizona before distributing them out of the Miami area. According to Forbes , Rodriguez's company, Wellness Fitness Nutrition LLC (WFN), had a client list that included "at least 50 customers in the Eastern District of New York." It was noted that the ring made over $10 million in the distribution of illegal steroids.